Vitamin B1 - Thiamine Pyrophosphate

Vitamin B1, Thiamine, is a water soluble vitamin necessary for oxidative carboxylation of pyruvate to acetate and acetyl coenzyme A, the primary substrate for the Krebs cycle. It also is the coenzyme for transketolase in the pentose phosphate pathway. Thiamine pyrophosphate is an activated coenzyme form of B1 and acts in decarboxylation and transamination metabolic reactions.

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